Mateen C. Moghbel, MD

Dr. Moghbel is a board-certified diagnostic radiologist and nuclear medicine physician specializing in oncologic imaging and radiopharmaceutical therapy. He earned his medical degree from the Stanford University School of Medicine and completed his diagnostic radiology residency along with fellowships in nuclear medicine and musculoskeletal imaging at Massachusetts General Hospital, a teaching hospital of Harvard Medical School. He holds dual board certifications from the American Board of Radiology and the American Board of Nuclear Medicine.

Dr. Moghbel has authored dozens of publications in peer-reviewed medical journals and has contributed to advances in numerous applications of PET imaging as well as the use of artificial intelligence in imaging interpretation. He is committed to working closely with patients and referring clinicians to provide precise, compassionate, and collaborative care of the highest quality.

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Educational Background and Early Career

  • Stanford University School of Medicine: M.D., Stanford, CA, 2018
  • University of Pennsylvania: B.A. in Neuroscience, Philadelphia, PA, 2013

Post-Graduate Training

  • Massachusetts General Hospital
    • Musculoskeletal Imaging Fellowship
    • Boston, MA, 2023-2024
  • Massachusetts General Hospital
    • Nuclear Radiology Fellowship
    • Boston, MA, 2023
  • Massachusetts General Hospital
    • Breast Imaging Fellowship
    • Boston, MA, 2022
  • Massachusetts General Hospital, Harvard Medical School
    • Diagnostic Radiology Residency
    • Boston, MA, 2019-2023
  • Kaiser Permanente Santa Clara Medical Center
    • Internal Medicine Internship
    • Santa Clara, СА, 2018-2019

Clinical Appointment

Massachusetts General Brigham, Department of Radiology

  • Attending Radiologist
  • Boston, MA, 2024-Present
  • Serve as an attending radiologist with appointments in the Nuclear Medicine division of Massachusetts General Hospital as well as the Musculoskeletal and Body Imaging divisions of the Enterprise Service Group of Massachusetts General Brigham

Board Certification

  • American Board of Nuclear Medicine: 2023-Present
  • American Board of Radiology: 2024-Present

Medical Licensure

  • Massachusetts Medical License: 2020-Present
  • New Hampshire Medical License: 2024-Present
  • California Medical License: 2024-Present

Affiliations

  • Radiological Society of North America (RSNA)
    • Member, March 2014 – Present
  • Society of Nuclear Medicine and Molecular Imaging (SNMMI)
    • Member, April 2014- Present
  • Current Molecular Imaging (CMI)
    • Editorial Board Member, 2014-2016

Professional Experience

  • Massachusetts General Hospital, Department of Radiology
    • Researcher
    • Boston, MA, 2019-Present
    • Served as an expert annotator and advisor in an industry-sponsored effort to develop an AI tool for quality assurance in screening mammography
    • Served as an expert annotator in the development of an AI tool for the detection of pulmonary nodules, culminating in publication in the Journal of the American Medical Association
    • Designed and implemented a PET imaging curriculum for diagnostic radiology residency program
  • MetroWest Imaging Center
    • Director of Moonlighting
    • Framingham, MA, 2022-2023
    • Led a team of five physicians responsible for identifying and managing intravenous contrast allergies and extravasations in patients undergoing imaging studies
  • Kaiser Permanente Medical Center, Department of Interventional Radiology
    • Researcher
    • Santa Clara, СА, 2018-2019
    • Authored multiple articles on complications associated with inferior vena cava filters, one of which received the Distinguished Clinical Study Award from the Journal of Vascular and Interventional Radiology
  • Stanford University Hospital, Department of Nuclear Medicine
    • Researcher
    • Stanford, CA, 2013-2018
    • Authored a series of invited review articles in the Journal of Nuclear Medicine on PET and CT imaging criteria for staging and assessing response to therapy in patients with lymphoma
    • Designed studies, collected and analyzed PET/CT data, and drafted manuscripts comparing various imaging criteria and investigating an automated approach to response assessment in lymphoma
  • Hospital of the University of Pennsylvania, Department of Radiology
    • Researcher
    • Philadelphia, PA, 2011-2013
    • Authored numerous journal articles, grant proposals, and book chapters on novel applications of PET imaging in various neurologic, oncologic, cardiovascular, endocrine, and inflammatory disorders
    • Published an article as first author that set a journal record for downloads, was cited in multiple media outlets, and was referenced in FDA reviews of Amyvid, the first clinically approved amyloid-PET agent
    • Led a team of four undergraduate students in collecting, quantifying, and statistically analyzing PET data for neuroimaging studies on Alzheimer’s disease, sleep apnea, smoking, chemotherapy, and epilepsy
  • Stanford University, Department of Biology
    • Teaching Assistant
    • Stanford, CA, 2014
    • Assisted in teaching an upper-level undergraduate biology course (BIO 258: Developmental Neurobiology) by leading weekly review session and journal clubs, participating in curriculum development, and grading assignments and exams

Publications

  • Leong S, Farzanegan F, Moghbel MC, Min J, Rajan S, Liu CM, Freed R, Loh S, Morshedi M, Rana R, Wang D, Howles-Banerji G, Bolanos F, & Wang SL. (2023). Complex inferior vena cava filter retrievals: success rate and predictors of adverse events at a large specialized referral center. American Journal of Roentgenology, 220(3), 389-397.
  • Homayounieh F, Digumarthy S, Ebrahimian S, Rueckel J, Hoppe BF, Sabel BO, Conjeti S, Ridder K, Sistermanns M, Wang L, Preuhs A, Ghesu F, Mansoor A, Moghbel M, Botwin A, Singh R, Cartmell S, Patti J, Huemmer C, Fieselmann A, Joerger C, Mirshahzadeh N, Muse V, & Kalra M. (2021). An artificial intelligence-based chest X-ray model on human nodule detection accuracy from a multicenter study. JAMA Network Open, 4(12), e2141096-e2141096.
  • Moghbel MC, Chen Z, Liu CM, Rajan S, Vempaty HT, & Wang SL. (2021). Thrombotic Risk Associated with Inferior Vena Cava Filter Placement in Patients with Heparin-Induced Thrombocytopenia. Journal of Vascular and Interventional Radiology, 32(12), 1629-1634.
  • Ayubcha C, Moghbel M, Borja AJ, Newberg A, Werner TJ, Alavi A, & Revheim, ME. (2021). Tau Imaging in Head Injury [Book chapter]. PET clinics, 16(2), 249-260.
  • Mayer M, Borja AJ, Hancin EC, Auslander T, Revheim ME, Moghbel MC, & Rajapakse CS. (2020). Imaging Atherosclerosis by PET, With Emphasis on the Role of FDG and NaF as Potential Biomarkers for This Disorder. Frontiers in physiology, 11, 1252.
  • Ayubcha C, Revheim ME, Newberg A, Moghbel M, Rojulpote C, Werner TJ, & Alavi A. (2020). A critical review of radiotracers in the positron emission tomography imaging of traumatic brain injury: FDG, tau, and amyloid imaging in mild traumatic brain injury and chronic traumatic encephalopathy. European Journal of Nuclear Medicine and Molecular Imaging, 1-19.
  • Ayubcha C, Newberg A, Torigian D, Zabrecky G, Monti D, Moghbel M, Werner T, Wintering N, & Alavi A. (2020). Application of a Global Derivation Segmentation Technique in mTBI: Optimizing Grey and White Matter Segmentation in PET/MR [Abstract]. Journal of Nuclear Medicine, 61 (supplement 1), 1404-1404.
  • Ayubcha C, Tran J, Torigian D, Moghbel M, Werner T, Alavi A, & Revheim ME. (2020). The Utility of PET/MRI in the Surgical Management of Brain and Vertebral Metastases [Abstract]. Journal of Nuclear Medicine, 61 (supplement 1), 1196-1196.
  • Ayubcha C, Kothekar E, Revheim ME, Moghbel M, Rojulpote C, Torigian D, Werner TJ, & Alavi A. (2020). Limitations of FDG-PET/MRI in the Detection and Characterization of Atherosclerosis [Abstract]. Journal of Nuclear Medicine, 61 (supplement 1), 1372-1372.
  • Al-Zaghal A, Aras M, Borja AJ, Moghbel M, Demir Y, Houshmand S, Ciftci E, Werner TJ, Høilund-Carlsen PF, Torigian DA, & Han Y. (2020). Detection of pulmonary artery atherosclerosis by FDG-PET/CT: a new observation. American Journal of Nuclear Medicine and Molecular Imaging, 10(3), 127.
  • Høilund-Carlsen PF, Moghbel MC, Gerke O, & Alavi A. (2019). Evolving role of PET in detecting and characterizing atherosclerosis. PET clinics, 14(2), 197-209.
  • Høilund-Carlsen PF, Alavi A, Moghbel MC, & Salavati A. (2019). PET-CT-MR Imaging-Based Cardiovascular Imaging. PET clinics, 14(2), xiii-xv.
  • Promteangtrong C, Kolber M, Ramchandra P, Moghbel M, Raja A, Houshmand S, Werner TJ, Vafaee MS, Majdi A, Alavi A. (2018). Novel Quantitative Approach in Functional and Structural Imaging of Brain in Normal Ageing and Neurodegenerative Disorders: Part I. Basic Considerations in PET and MRI. Journal of Experimental and Clinical Neurosciences, 5(1), 1-9.
  • Baratto L, Davidzon GA, Moghbel M, Hatami N, Iagaru A, Mittra ES. (2018). Comparison Between Different PET and CT-Based Imaging Interpretation Criteria at Interim Imaging in Patients With Diffuse Large B-Cell Lymphoma. Clinical Nuclear Medicine, 43(1), 1-8.
  • Torigian, DA, Green-McKenzie, J, Liu, X, Shofer, FS, Werner, T, Smith, CE, Strasser AA, Moghbel MC, Parekh AH, Choi G, Goncalves, MD. (2017). A study of the feasibility of FDG-PET/CT to systematically detect and quantify differential metabolic effects of chronic tobacco use in organs of the whole body-a prospective pilot study. Academic Radiology, 24(8), 930-940.
  • Moghbel MC, Mittra E, Gallamini A, Niederkohr R, Chen DL, Zukotynski K, Nadel H, Kostakoglu L. (2017). Standardized Response Assessment Criteria and their Applications in Lymphoma: Part 2. Journal of Nuclear Medicine, 58(1):13-22.
  • Moghbel MC, Kostakoglu L, Gallamini A, Niederkohr R, Chen DL, Zukotynski K, Nadel H, Kostakoglu L, Mittra E. (2016). Standardized Response Assessment Criteria and their Applications in Lymphoma: Part 1. Journal of Nuclear Medicine, 57(6), 928.
  • Moghbel MC, Alavi A, Torigian DA. (2016). PET/MR: Concept and Clinical Application [Book chapter]. Saba L (Ed.). Magnetic Resonance Imaging Handbook: Imaging of the Pelvis, Musculoskeletal System, and Special Applications to CAD. Taylor & Francis.
  • Moghbel M, Newberg A, Alavi A. (2016). Positron Emission Tomography: Ligand Imaging [Book chapter]. Masdeu J, Gonzalez RG (Ed.). Handbook of Clinical Neurology: Neuroimaging, Part I. Elsevier.
  • Moghbel MC, Newberg A, Serruya M, Alavi A. (2015). SPECT and PET Imaging of Neurotransmitters in Dementia [Book chapter]. Kanekar S (Ed.). Imaging of Neurodegenerative Disorders. Thieme.
  • Parsons MA, Moghbel M, Saboury B, Torigian DA, Werner TJ, Rubello D, Basu S, Alavi A. (2015). Increased 18F-FDG uptake suggests synovial inflammatory reaction with osteoarthritis: preliminary in-vivo results in humans. Nuclear Medicine Communications, 36(12), 1215-1219.
  • Promteangtrong C, Kolber M, Ramchandra P, Moghbel M, Houshmand S, Schöll M, Bai H, Werner TJ, Alavi A, Buchpiguel C. (2015). Multimodality Imaging Approach in Alzheimer disease. Part I: Structural MRI, Functional MRI, Diffusion Tensor Imaging and Magnetization Transfer Imaging. Dementia & Neuropsychologia, 9(4), 318-329.
  • Promteangtrong C, Kolber M, Ramchandra P, Moghbel M, Houshmand S, Schöll M, Bai H, Werner TJ, Alavi A, Buchpiguel C. (2015). Multimodality Imaging Approaches in Alzheimer’s disease. Part II: 1H MR spectroscopy, FDG PET and Amyloid PET. Dementia & Neuropsychologia, 9(4), 330-342.
  • Saboury B, Parsons MA, Moghbel M, Rubello D, Brothers A, Torigian DA, Werner TJ, Houshmand S, Basu S, Lam MG, Alavi A. (2015). Quantification of aging effects upon global knee inflammation by 18F-FDG-PET. Nuclear Medicine Communications, 37(3), 254-258.
  • Mota LG, de Barros AL, Fuscaldi LL, de Souza CM, Cassali GD, Moghbel M, Alavi A, Rubello D, Fernandes SO, Oliveira MC, Cardoso VN. (2015). Evolving role of radiolabeled particles in detecting infection and inflammation, preliminary data with 99mTc-phytate in rats. Nuclear Medicine Communications, 36(11), 1113-1119.
  • Fernandes RS, Mota LG, Kalbasi A, Moghbel M, Werner T J, Alavi A, Rubello D, Cardoso VN, de Barros ALB. (2015). 99mTc-phytate as a diagnostic probe for assessing inflammatory reaction in malignant tumors. Nuclear Medicine Communications, 36(10), 1042-1048.
  • Hess S, Basu S, Blomberg BA, Lam M, Moghbel MC, Zhu HJ, Mirzaei S, Alavi A, Hoilund-Carlsen PF. (2015). The FDG-PET Revolution of Medical Imaging-Four Decades and Beyond. Current Molecular Imaging, 4(1), 2-19.
  • Pasha AK, Moghbel M, Saboury B, Gharavi MH, Blomberg BA, Torigian DA, Kwee TC, Basu S, Mohler IE, Alavi A. (2014). Effects of age and cardiovascular risk factors on ($^{18}$F-FDG PET/CT quantification of atherosclerosis in the aorta and peripheral arteries. Hellenic Journal of Nuclear Medicine, 18(1), 5-10.
  • Masangkay N, Basu S, Moghbel M, Kwee T, Alavi A. (2014). Brain $^{18}$F-FDG-PET characteristics in patients with paraneoplastic neurological syndrome and its correlation with clinical and MRI findings. Nuclear Medicine Communications, 35(10), 1038-1046.
  • Sorokin J, Saboury B, Ahn JA, Moghbel M, Basu S, Alavi A. (2014). Adverse functional effects of chemotherapy on whole-brain metabolism: a PET/CT quantitative analysis of FDG metabolic pattern of the “chemo-brain”. Clinical Nuclear Medicine, 39(1), e35-e39.
  • Blomberg BA, Moghbel MC, Saboury B, Stanley CA, Alavi A. (2013). The Value of Radiologic Interventions and $^{18}$F-DOPA PET in Diagnosing and Localizing Focal Congenital Hyperinsulinism: Systematic Review and Meta-Analysis. Molecular Imaging and Biology, 15(1), 97-105.
  • Moghbel MC*, Kepe V*, Längström B, Zaidi H, Vinters HV, Huang SC, Satyamurthy N, Doudet D, Mishani E, Cohen RM, Høilund-Carlsen PF, Alavi A, Barrio JR. (2013). Amyloid-β positron emission tomography imaging probes: a critical review. Journal of Alzheimer’s Disease, 36(4), 613-31.
  • Blomberg BA, Moghbel MC, Alavi A. (2012). PET imaging of -cell mass: is it feasible?. Diabetes/Metabolism Research and Reviews, 28(7), 601-602.
  • Moghbel MC*, Saboury B*, Basu S, Alavi A (2012). Modern Quantitative Techniques for PET/CT/MR Hybrid Imaging [Book chapter]. Schaller B (Ed.). Molecular Imaging (pp. 1-12). InTech.
  • Moghbel MC*, Saboury B*, Basu S, Metzler SD, Torigian DA, Långström B, Alavi A. (2012). Amyloid-β imaging with PET in Alzheimer’s disease: is it feasible with current radiotracers and technologies?. European Journal of Nuclear Medicine and Molecular Imaging, 39(2), 202-208.
  • Parekh A, Kim A, Saboury B, Moghbel MC, Alavi A, Schwab R. (2012). Reduced metabolism in the cerebellum of obstructive sleep apnea (OSA) patients using FDG-PET [Abstract]. Journal of Nuclear Medicine, 53(supplement 1), 2222-2222.
  • *Co-first authorship

Presentations

  • Comparison of the Predictive Value of FDG-PET and CT-Based Response Assessment Criteria in Diffuse Large B-Cell Lymphoma [Poster Presentation]. 2016. Stanford University, Stanford, CA.
  • The Effects of Chronic Smoking on Cerebral Metabolism, as Evaluated by FDG-PET Imaging [Invited Lecture]. 2012. Neuroscience Research Institute, Gachon University. Incheon, South Korea.

Awards & Honors

  • Award for Distinguished Clinical Study, Journal of Vascular and Interventional Radiology: 2021
  • Alavi-Mandell Award, Society of Nuclear Medicine & Molecular Imaging: 2018
  • Stanford University Research Symposium Award: 2016
  • University of Pennsylvania Rose Research Award: 2013
  • Phi Beta Kappa, University of Pennsylvania: 2013
  • Summa Cum Laude, University of Pennsylvania: 2013

Contact Information

Dr. Mateen C. Moghbel, MD

Located at:
350 Third St, Unit 509,
Cambridge, MA 02142

Phone: (215) 586-1129
Email: mateenmoghbel@gmail.com